Morgellons History

Scientific Studies

Treatments

Morgellons Specimens

Videos About Morgellons

http://www.nature.com/gt/journal/v11/n1s/full/3302364a.html

• 1.  Introduction
• 2.. Characteristics of Morgellons
• 3.  Is Morgellons a Man-Made Condition?
• 4.  Fibers
• 5.  Bacteria
• 5.  Crystals and Hexagons
• 6.  Man-made objects, robots, machines and electronics
• 7.  Diseased hair or hair loss
• 8.  Diseased skin
• 9.  Diseased blood
• 10.  Inability to think clearly people call "brain fog"
• 11.  Animals and arthropods in skin, hair, eyes
• 12  Nanobiology and Materials
  
• 13. History of Morgellons
  
• 15. Scientific studies on Morgellons
• 16. Morgellons specimen
• 17. Treatment or Cure
• 18. Morgellons Websites

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3910909/

 

See https://en.wikipedia.org/wiki/Helminthic_therapy

So how do you get froman insect “bite” to Morgellons?

The video shows the various kinds of fibers that have emerged from Morgellons victim's skin. Some of what people think are fibers are really worms.  People have never heard of growing colored or glowing fibers in their skin and they surely have never had to identify them by name. These kinds of infections are just not heard of in America because this kind of bioweapon has never occurred here.

WHAT ARE CYCLODEXTRINS?
Cyclodextrans are a family of compounds made up of sugar molecules bound together in a ring (cyclic oligosaccharides). Bacillus macerans and circulans naturally make cyclodextrans. Cyclodextrins are able to form host-guest complexes with hydrophobic molecules given the unique nature imparted by their structure. There are molecules which induce cyclization and stacking of the tiny “cups” and they form a filament when many are stacked together. There is a channel in the middle where harmful proteins may be placed. Cyclodextrins are used to separate molecules by trapping one kind of molecule and leaving others free.
Cyclodextrins are shaped like cups with a hole in the bottom.
This diagram shows a cyclodextrin separating a dye molecule.
This demonstrates Fluorescence Quencching
 

One Morgellons study found 6 bacteria. Bacteria is known to possess the amazing ability to create plastic and metal, even gold. Consider the following:
 

BACTERIA MAKE THE DNA HYDROGEL?
One emerging method for the production of complex materials is by genetically engineering bacteria to express recombinant protein polymers. The general process for making biosynthetic polymers begins with designing a DNA gene, which encodes for a specific amino acid sequence. The DNA is chemically synthesized and then inserted into a cloning vector by a series of slicing and ligating reactions. The gene is placed into an expression vector which can be taken up by an acceptor cell in a host microorganism such as E. coli. The protein encoded by the DNA template, is transcribed into mRNA using the host system’s natural machinery. The mRNA serves as a template for the host ribosomes to construct the synthetic protein.
http://udini.proquest.com/view/highly-modular-protein-polymers-for-goid:304480457/
 

WHAT ARE THE OBVIOUSLY
MAN-MADE STRUCTURES?
Microbes can be encoded with instructions to express a gene or to perform an activity, you can understand how they can construct objects that look like mica, pieces of metal and plastic.
This article shows you that these things are possible and states the names of the scientists who have made them possible.
Microbial Materials: Scientists Co-opt Viruses,
Bacteria, and Fungi to Build New Structures
This is a recent finding from a Morgellons victim. Some specimen are man-made and some are made by microbes. It is difficult telling which is which.
This shows a microbial product which has pushed its way to the surface of a woman’s toe.

This is a closer look at the object. It came to the surface of the skin and fell off. I think this indicates a colony of bacteria producing mycotoxins in the skin.
This is an internet picture of what was labeled mycotoxins. It looks like a miniature collection of dirt and sticks.

These two specimens exited a toe.
It looks like some ribbon-like twisted blue fibers.


These fluorescent shapes are biological weapons: .
This is enlarged from previous picture.
 

ANIMALS
[Picture 309] Size. Morgellons victims have symptoms of biting and crawling insects and sores in their skin. If it feels like a bug, its probably a bug. There are plenty of Morgellons victims taking pictures of the animals they find in their skin so labeling the victims as delusional is mute. The thing that makes the presence of animals so deniable is that they cannot be seen because of their size. The larger animals such as gnats and mosquitos can be seen but most are too small to be seen and some of them are transparent, such as mites and nematodes. A microscope is needed to enlarge them from 200X-400X or more see them.
Identification. The other problem is that people have no experience identifying microscopic animals only known to the scientists who study them. Dummy doctors deny these animals exist and refuse to use a microscope to look at them. How do doctors get through medical school without using a microscope?
Springtail?
 
This is a Morgellons’s victims hair with little glowing
organism living inside in a separate tiny filament.
 
Transparent Morgellons Mite?
It is missing some legs due
to some difficulty capturing it.
 

ARTICLES ON BIOWARFARE:
Protein Engineering: Security Implications
ttp://tinyurl.com/dyugkzr
Living Nightmares: Biological Threats
Enabled by Molecular Biology
http://tinyurl.com/ce2rnsj

ORGANISMS WITH GENOMES SEQUENCED
Morgellons animals also coincide with some organisms whose genomes have been sequenced.Genetic information is needed to create a transgenic organism. A transgenic organism is one which expresses the genes of another species. Genes can be taken from a fluorescent jellyfish and put into a rabbit to make it glow. There are several ways to introduce new genes. In one method genetic instructions are incorporated into a circular structure found in cells called a plasmid. The plasmid copies itself into host cells. Genes for virulence can be taken from B. anthrax and put into B. subtilis. Genes for making cyclodextrins can be taken from B. macerans or B. circulans and put into E. coli to create a super duper cyclodextrin fiber-making bacteria.
Porcellio scaber or wood louse
Genome Complete Morgellons specimen
 

MODEL ORGANISMS
There are certain themes in the specimens found in Morgellons. One of them is model organisms which are non-human species that are extensively studied with the expectation that discoveries made in the organism model will provide insight into how other organisms work. Scientists have been using model organisms for genetic research. Among the specimen found in Morgellons are model organisms such as Drosophila melanogaster, Caenorhabditis elegans, Tobacco mosaic virus, Escherichia coli, Bacillus subtilis, Mycoplasma genitalium, Aliivibrio fischeri, Dictyostelium discoideum, and others http://en.wikipedia.org/wiki/Generic_Model_Organism_Database
Model Organism: Nasonia
Morgellons Specimen of parasitic wasp
 

This unidentified insect [black fungus gnat?] came
from a Morgellons victim’s scalp carrying a “package” of eggs.
Chapter 2: The Dynamics of Arthropod Borne Diseases http://tinyurl.com/bqdxjau
Flying Vaccination A Transgenic Mosquito
Delivers a Leishmania Vaccine Via Blood Feeding

http://tinyurl.com/bodf8ly
BIOWEAPON
The history of bioweapons shows that live organisms have often been used as stealthy deniable weapons to debilitate and kill an enemy. As a torture weapon, Morgellons is perfect. The unsightly bloody sores, the loss of hair and worms under the skin take away the sense that you are okay. The victim loses even the comfort of a hug from a husband or children in order to keep them from getting the disease. They stop going outside their homes, they lose their jobs and their property.

This subject got political very quickly. But who is the enemy if innocent civilians are the ones being attacked and are suffering? I don’t see the president suffering, or the senate or congress. Why would governments want to hurt their own citizens? As an aggressor they would want their enemy to be powerless to fight back. Its easier to subdue the enemy if they don’t even know they are the enemy. War was declared on the American people on 9-11 with the fake “war on terror.”

Morgellons points its itchy fingers to the culprits but nobody is listening. Society has not been disrupted enough for mainstream deities to be concerned which is a factor when designing a bioweapon. As a Bioweapon, the longer a disease goes without treatment, the more potent it will be as a weapon. The byword is delay. Delay diagnosis, delay research, delay treatment. Mislabeling and denying that Morgellons exists suits the formidable aggressor who wants to see the full effect of their lethal and potent stealth weapon. Their victims are defenseless.
 

INSECTS AND MAN-MADE OBJECTS
Various man-made objects are found in Morgellons so it can be deducted that the fibers are engineered by humans. Some hair and fibers even have the names of corporations and individuals.Why would someone want to put fibers in another person’s skin? Who are these people? What is the purpose of the fibers? How are the fibers generated? Are they alive? Is there something alive inside the fibers? Do only people with Morgellons have these fibers? Are the fibers infectious? Can other people get sick from them? How do you get rid of them?I have the view that examining the fields of science which have the capability of creating them can answer these questions. The research has already been done to create Morgellons.What fields of science are concerned with biology and technology? Biotechnology. What science is concerned with insects? Entomology. What science has introduced new materials to these fields? Synthetic Biology.Synthetic materials can be made bio-compatible for use in the medical field. When I compared the specimen from hundreds of people and compared the technology that made them possible, I realized that people had been inoculated with synthetic materials by transgenic organisms. The “flying vaccine”, which is a method invented to deliver vaccines by mosquitos, doesn’t necessarily have to fly. That method was deemed unethical. That doesn’t mean it hasn’t been used on helpless citizens.
 

THE RED WINE TEST

Red wine contains glycoproteins and sugars. These are what the Scripps Lab and Peter Schultz have been engineering with synthetic amino acids. Bacterial colonies use these to reproduce or create a viral protein product. When body fluids containing microbes and DNA hydrogels are fed red wine and cultured, after a time filamentation occurs during stress [the food runs out in the culture?]. That may be what people are seeing with that test (Clifford Carnicom). You can see the protein crystals in the picture to the right. The man who took these pictures does not have a microscope but is getting one. However, there is more to think aabout.

An enzyme called glycosyltransferase converts starch into cyclodextrins which are some of the fibers in Morgellons. Glycosyl transfer can be carbohydrate, glycoside oligosaccharide or a polysaccharide. Glycosyl transfer can also occur to protein residues, usually to tyrosine, serine, or threonine to give O-linked glycoproteins or to asparagine to give N-linked glycoprotins, which are used to make DNA. Glycoproteins are important for white blood cell recognition. Some glycoproteins in the immune system are antibodies and other molecules are part of the immune response.

There are glycoproteins attached to blood cells which determine what blood type you are. The ABO blood group system is determined by what type of glycosyltransferases are expressed in the body. Engineering glycosyltransferases is involved in making changes in the blood which is obviously happening in Morgellons victims. There are chemical and photo switches being built into synthetic materials and one could imagine turning someone’s switch off to eliminate them without a weapon or radiate them to initiate gene therapy with intelligent polymers. i can only guess but you could go ask Peter G. Schultz. My question is: Is what is in the blood a “system” according to hierarchy of synthetic biology above? So many questions!

GLYCOPROTEINS AND ABO BLOOD GROUPS
Unnatural Amino Acids have also been used to create Synthetic Red Blood Cells and Platelets. These are the people who designed the blood changes:

SYNTHETIC BLOOD PLATELETS DEVELOPED
[Synthetic Blood Cells] Mitragotri, his research group, and their collaborators from the University of Michigan succeeded in synthesizing the particles by creating a polymer doughnut-shaped template, coating the template with up to nine layers of hemoglobin and other proteins, then removing the core template. The resulting particles have the same size and flexibility, and can carry as much oxygen, as natural red blood cells. The flexibility, absent in “conventional” polymer-based biomaterials developed as carriers for therapeutic and diagnostic agents, gives the sRBCs the ability to flow through channels smaller than their resting diameter, stretching in response to flow and regaining their discoidal shape upon exiting the capillary, just as their natural counterparts do.
 

DNA POLYMER GENE THERAPY
IN THE BLOOD:
INTELLIGENT POLYMERS AS NONVIRAL VECTORS
The successful gene therapy largely depends on the vector type that allows a selective and efficient gene delivery to target cells with minimal toxicity. Nonviral vectors are much safer and cheaper, can be produced easily in large quantities, and have higher genetic material carrying capacity. However, they are generally less efficient in delivering DNA and initiating gene expression as compared to viral vectors, particularly when used in vivo. As nonviral vectors, polycations may work well for efficient cell uptake and endosomal escape, because they do form compact and smaller complexes with plasmid DNA and carry amine groups, which give positive charge and buffering ability that allows safe escape from endosome/lysosome. However, this is a disadvantage in the following step, which is releasing the plasmid DNA within the cytosol. In order to initiate transcription and enhance gene expression, the polymer/plasmid complex should dissociate after releasing from endosome safely and effectively. There are also other limitations with some of the polycationic carriers, for example, aggregation, toxicity, etc. Intelligent polymers, also called as ‘stimuli responsive polymers’, have a great potential as nonviral vectors to obtain site-, timing-, and duration period-specific gene expression, which is already exhibited in recent studies that are briefly summarized here.

PEGylated DNA/transferrin-PEI complexes:    reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery.

SYNTHETIC PROTEINS IN HUMAN BLOOD
These unnatural amino acids are being coded into all parts of the blood as you can see the patent to the right. With this weapon, you can rule the world. Blood is so complicated that there must be many ways to genetically code someone out of existence, one way being to not hold myoglobin in the muscles, or not to carry oxygen in hemoglobin. Check out these two patents. The research is done with government grants. Its not difficult to comprehend the consequences.
In vivo incorporation of unnatural amino acids http://www.freepatentsonline.com/y2008/0227152.html
Inventors: Schultz, Peter (La Jolla, CA, US), et al.
Abstract. The invention provides methods and compositions for in vivo incorporation of unnatural amino acids. Also provided are compositions including proteins with unnatural amino acids.

WHAT ARE THE GELS?
The Cornell group has developed DNA hydrogels that are made entirely from DNA. Biological components can be easily encapsulated in these gels during the enzymatic gelation process which is performed under physiological conditions. The DNA hydrogels can be easily tuned by adjusting initial concentrations and using different types of branched DNA monomers, allowing them to be tailored for specific applications such as controlled drug delivery, tissue engineering, 3D cell culture, cell transplant therapy and other biomedical applications.
The DNA hydrogels provided the foundation for our newly developed cell free expression system which we call the P-gel system. In this system, a linear expression plasmid is incorporated into a DNA hydrogel by using branched DNA monomers as croslinkers.  The resulting P-gel is molded into micropads which are used in place of plasmid DNA during coupled transcription/translation cell free expression. The P-gel system can produce up to 5 mg/ml of protein in a single expression, a vast improvement over commercially available solution phase systems.
http://luolabs.bee.cornell.edu/gel.html
The picture on the left is a drawing by the Cornell group of the structures created by synthetic hydrogels. In the right hand picture, the hydrogels have been combined with human blood in a Morgellons victim. You can see the X’s, Y’s and T’s.
 

THE SCIENCE OF PROTEINS
A few preliminary ideas must be considered to understand where the fibers come from. They are the synthetic product of a living system, a combination of cyclization and synthetic polymers. The bacteria produces cyclic fibers, some containing bioactive inclusions.
Genetically encoded initiator for
polymer growth from proteins
http://tinyurl.com/caw62al
In vivo production of cyclic peptides or
inhibiting protein-protein interaction
http://tinyurl.com/ca3goq2
Structures of Naturally Occurring
Circular Proteins from Bacteria
http://tinyurl.com/br2sdyb
 …circular proteins fundamentally different from the nonribosomal cyclic peptides have been discovered. These molecules are true proteins in that they have a well-folded three-dimensional structure and are produced via translation of genes…produce a seamless circle of peptide bonds. Such circular proteins occur in a diverse range of organisms, from bacteria to plants and animals, but the focus here is on circular proteins produced by bacteria.
 

The Evolution of Proteins with Genetically
Encoded “Chemical Warheads”
http://tinyurl.com/c57jsmx
The Genetic Codes
http://tinyurl.com/d3j3md
Synthetic Pair Used in Human Transfection The orthogonal pairs of synthetase and tRNA which work for one organism may not work for another as the synthetase may mis-aminoacylate endogenous tRNAs or the tRNA be mis-aminoacylated itself by an endogenous synthetase. As a result the sets created to date differ between organisms.
orthogonal sets in E. coli
tRNATyr-TyrRS pair from the archaeon Methanococcus jannaschii
tRNALys–LysRS pair from the archaeon Pyrococcus horikoshii
tRNAGlu–GluRS pair from Methanosarcina mazei
leucyl-tRNA synthetase from Methanobacterium thermoautotrophicum and a mutant leucyl tRNA derived from Halobacterium sp
orthogonal sets in yeast
tRNATyr-TyrRS pair from Escherichia coli
tRNALeu–LeuRS pair from Escherichia coli
tRNAiMet from human and GlnRS from Escherichia coli
orthogonal sets in mammalian cells
tRNATyr-TyrRS pair from Bacillus stearothermophilus
modified tRNATrp-TrpRS pair from Bacillus subtilis trp
tRNALeu–LeuRS pair from Escherichia coli
 Site-specific incorporation of an unnatural amino acid into proteins in mammalian cells

SYNTHETIC BIOLOGY
Using modern genetic engineering techniques, man-made amino acids can be inserted into the genomes of organisms, from archea, fungi, plants, and bacteria to humans. Synthetic DNA-polymer/dye conjugates can be transfected into humans using these techniques. There are some Morgellons victims whose skin glows or blinks. Blinking can be accomplished by incorporating 57(?) Biobricks.[1] Foreign DNA and synthetic polymers can be carried across the blood brain barrier which may be responsible for symptoms of brain fog and fatigue in people who have Morgellons.
 

The Bacterial Nanorecorder: Engineering E. coli to
Function as a Chemical Recording Device
http://tinyurl.com/cs65sc8
Synthetic biology is an emerging branch of molecular biology that uses synthetic genetic constructs to create man-made cells or organisms that are capable of performing novel and/or useful applications. Using a synthetic chemically sensitive genetic toggle switch to activate appropriate fluorescent protein indicators (GFP, RFP) and a cell division inhibitor (minC), we have created a novel E. coli strain that can be used as a highly specific, yet simple and inexpensive chemical recording device. This biological “nanorecorder” can be used to determine both the type and the time at which a brief chemical exposure event has occurred. In particular, we show that the short–term exposure (15–30 min) of cells harboring this synthetic genetic circuit to small molecule signals (anhydrotetracycline or IPTG) triggered long-term and uniform cell elongation, with cell length being directly proportional to the time elapsed following a brief chemical exposure. This work demonstrates that facile modification of an existing genetic toggle switch can be exploited to generate a robust, biologically-based “nanorecorder” that could potentially be adapted to detect, respond and record a wide range of chemical stimuli that may vary over time and space.
 

PATENT FOR CROSSING BLOOD BRAIN
BARRIER WITH SYNTHETIC MATERIALS
Genetically encoded multifunctional compositions bidrectionally transported between peripheral blood and the cns
http://tinyurl.com/ckqrxkk
Abstract: Provided herein are compositions for increasing transport of agents across the blood-brain barrier, in some embodiments in both directions, while allowing their activity once across the barrier to remain substantially intact. The agents are transported across the blood-brain barrier via one or more endogenous receptor-mediated transport systems. In some embodiments the agents are therapeutic, diagnostic, or research agent. Also provided herein are nucleic acids encoding proteins contained in the compositions
Plasmid in upper right corner is inserted in bacterial cell to tranform into transgenic organism.The materials used in this science are found in the Principles of Gene Manipulation and Genomicsby Primrose and Twyman. Chapter 12 lists the materials used. I can’t locate the link to this. I can send you the pdf if you send me a comment.
This is a sample picture of a plasmid  used in
synthetic biology to incorprorate unnatural amino acids.
 

EXPANDED GENETIC CODE
AND ALLOPROTEINS
An expanded genetic code refers to an artificially modified genetic code using man-made amino acids in addition to the standard 20 amino acids which are nature’s building blocks of all proteins in humans. Proteins with non-natural amino acids are called alloproteins. An expanded genetic code allows modifications to be carried out in vivo, which means in the whole living organism or in latin “in a living thing there is truth” which is a play on words from in vino veritas “in wine there is truth”.

This efficient method of genetically directing insertion of unnatural proteins into natural proteins allows:
Genetic Coding with Fluorescent Proteins: Structure and function is studied using amino acids with slightly different size such as o-Methyltyrosine or dansylalanine instead of tyrosine, and by inserting genetically coded reporter moieties or fluorescent groups (color-changing and/or spin-active) into selected protein sites, chemical information about the protein’s structure and function can be measured.

Identifying and Regulating Protein Activity: by using photocaged aminoacids, protein function can be “switched” on or off by illuminating the organism. Thse are photo-reactive linkers (photocrosslinkers).
Changing the mode of action of a protein: one can start with the gene for a protein which binds a certain sequence of DNA, and, by inserting a chemically active amino acid into the binding site, convert it to a protein which cuts the DNA, rather than binding it. These are molecular switches which operate in signaling pathways.

Improving immunogenicity and overcoming self-tolerance: by replacing strategically chosen tyrosines with p-nitro phenylalanine, a tolerated self-protein can be made immunogenic (prion proteins are self-proteins).
Alloproteins can be used as molecular switches for signal pathways, as photocrosslinkers, or as fluorescently labeled probes. They can be used to clandestinely change the function and structure of a person’s proteins.
An example of the possible application for this method is biomedical where “chemical warheads” can be added to protein which target specific cellular components.
 

Ribbon Diagram of Green Fluorescent Protein
 
Aequorea victoria
The green fluorescent protein (GFP) refers to the protein first isolated from the jellyfish Aequorea victoria. The GFP gene can be introduced into organisms and maintained in their genome through injection with a viral vector or cell transformation. The GFP gene is used as a reporter of expression which identifies and measures a certain gene that has been taken up by or expressed in the cell or organism. As in the article to the left, GFP is used in synthetic biology. The GFP gene can be attached to bacterial genes and expressed in living cells of an entire organism. They express various colors depending on the unnatural protein attached and the wavelength of light reflected. This makes them biosensors (identify and measure).
Fluorescent Dyes-Scripps Lab diagram
GENETICALLY ENCODED
FLUORESCENT PROTEINS

 

 SYNTHETIC BIOLOGY COMES OF AGE
SYNTHETIC BIOLOGY COMES OF AGE POSTER
Bionic Bacteria May Help Fight
Disease and Global Warming
In 2001, scientists created bacteria with “unnatural” amino acids that glow, artificial additions to the 20 naturally occurring amino acids used as biological building blocks – into proteins at multiple sites. In 2007, they first used the technique in mammalian cells. They did this by creating an “expanded genetic code,” overriding the genetic code of the cells and instructing them to use the artificial amino acids in the construction of proteins.
WHY CHANGE HUMAN PROTEINS?
The next article explains the motivation for changing the proteins of the population of humans throughout the world. Proteins are just simply too complicated and synthetic biology makes it easier for humans to engineer clandestine death.
Evolution is not fast or efficient enough for engineers who plan to move blocks of genes around as routinely as they do electronic parts.
Life Redesigned to Suit the Engineering Crowd
Abstraction hierarchies are a human invention designed to assist people in engineering very complex systems by ignoring unnecessary details.  If the process to design a biological system was to write down the string of nucleotides, it would immediately become untenable even for experts to design anything but very simple systems.  Most people just aren’t capable of processing that kind of detail all at once.  If instead, an abstraction hierarchy is specified, it allows the designer of a biological system to ignore some of the implementation details and focus only on the high-level design issues

 

The Synthetic Hierarchy
ELEMENTS->NETWORKS->ORGANISMS->SYSTEMS
ELEMENTS:  Fundamental building blocks that provide primitive functionality (works like switches, oscillators in computers).
NETWORKS:  Interacting synthetic elements (regulatory networks of synthetic genes and promoters designed to induce transcription when triggered by external stimuli).

ORGANISMS:  Living machines assembled from synthetic elements.
SYSTEMS:  Multiple genetic machines working synchronously to achieve a complex goal.
Engineers called biosynthesists are reassembling sets of genes to fashion novel metabolic pathways, build new microbes and even rewrite the genetic code.

Recent feats of genetic manipulation include the development of standardized genetic parts called “BioBricks,” and microbes containing a mix of genes enabling them to make a chemical precursor of the anti-malarial drug, artemisinin.
Biosynthesists are also encoding microbes to produce proteins built from unnatural amino acids, designing bacteria to produce hydrogenbased alternative fuels, and yeasts that make ethanol from cellulose.
Recognizing that synthetic biology is not risk free, biosynthesists drafted the SB2 Declaration, suggesting ways to monitor and regulate this new field.

US Dept of Defense Highlighting Synthetic
Biology as a Research Priority
The Department of Defense will spend over $2 billion in 2012 on synthetic biology, modeling human behavior (for gangstalking strategies?), engineered materials (to drop on people from the sky or poison them in their homes?), cognitive neuroscience (control people’s brains), quantum materials and nano-science engineering, and is “working to find discriminators that open up the best capabilities for U.S. warfighters.”

Synthetic Biology and Defense
“Among the areas that are fast becoming a priority for the Pentagon is synthetic biology, which seeks to build new organisms or re-engineer existing ones to perform specific functions…the Pentagon is interested in understanding “how organisms sense and respond to stimuli — such as chemicals, ions and metals, or electrical,  magnetic, optical and mechanical impulses — at a genetic level”. That knowledge could help researchers to design “living sentinels”  that can monitor the presence of explosives or chemical pollutants. “We  can also develop tools that will allow us to detect adversarial uses of  synthetic biology,”…the Office of Naval Research in Arlington,  Virginia, is looking at how to biosynthesize targeted antibiotics that work by sensing and attacking specific pathogens. President Barack Obama’s proposed budget for next year would also provide $20 million to  the Defense Advanced Research Projects Agency (DARPA),another research arm of the Pentagon, to fund work in synthetic biology.”
The General Aggression Model as a
Framework for Understanding Torture and Genocide
by Arlin James Benjamin, Jr. “Victim  blame…Haritos-Fatouros (2003) observes a similar phenomenon among Greek torturers. The psychological function of blaming victims of torture for their humiliation is to make the torture victim appear less than human..In fact, such victim blame is likely facilitated by techniques in which the victims’ pain or humiliation appears self-inflicted (McCoy, 2006). Furthermore, the central assumption made by torturers of their victims’ guilt – the victims are  typically referred to as “terrorists”, “guerillas”, or “insurgents” …By releasing the psychological constraints regarding how to treat fellow human  beings, torturers find it easier to engage in the cruel treatment of their victims.
 

Horizontal gene transfer. The trans-kingdom gene transfer apparatus of Agrobacterium and the conjugative systems of bacteria are both involved in transporting macromolecules, not just DNA but also protein, across cell membranes into the nucleus of cells. Agrobacterium has transformed at least 80 different non-plant species including soil living bacteria, yeasts, fungi, algae, mammalian and human cells Its transformation is much like conjugation, the normal mating process between bacteria which can serve as the “helper,” creating new and exotic diseases. Agrobacterium-mediated transformation is the method of choice for the transformation of various fungi as transformation efficiencies are much higher than with other methods and the transformation protocols are relatively facile. Agrobacterium can transfer not only DNA but also proteins to the host organisms through its type four secretion system. This protein transfer has been shown for both plants and the yeast Saccharomyces cerevisiae. . [5]Agrobacterium-mediated Transformation of Nonplant Organisms.  Agrobacterium-mediated transformation is the method of choice for the transformation of various fungi. Agrobacterium can transfer not only DNA but also PROTEINS to the host organisms through its type four secretion system.
 

BioBricks. I have included this information here because Agrobacterium vector has a BioBrick cloning site built into the plasmid. This makes it easy to accomplish goals related to synthetic constructions and unusual shapes and objects found in Morgellons victims. Build it with BioBricks  and it like magic appears after it is constructed in the person’s body without their knowledge or consent. [5] pORE Open Series Vector with BioBrick sites, http://2010.igem.org/Team:Harvard/parts

WHAT ARE INCLUSION BODIES?
Inclusion bodies are nuclear or cytoplasmic aggregates of viral products in a bacterium or a eukaryotic cell and usually consist of viral capsid proteins. These can be biologically active which means they are able to affect cells of living organisms.
Morgellons Inclusion Bodies and Internet picture

Active inclusion body formation using Paenibacillus polymyxa PoxB as a fusion partner in Escherichia coli.
Abstract. Overexpression of Paenibacillus polymyxa PoxB in Escherichia coli induced the formation of inclusion bodies. An enzyme assay showed that the inclusion bodies exhibited PoxB activity, indicating that they were biologically active. Fusion of GFP and Bacillus subtilis AmyE to the C-terminus of the PoxB also induced the formation of biologically active aggregates when they were overexpressed in E. coli. Therefore, P. polymyxa PoxB can be used as a fusion partner to promote the formation of active inclusion bodies in E. coli.
http://www.ncbi.nlm.nih.gov/pubmed/14574705

Baculoviral polyhedrin as a novel fusion partner for formation of inclusion body in Escherichia coli
Seo JH et al.; Baculoviral polyhedrin, which originated from Autographa californica nuclear polyhedrosis virus (AcNPV), was employed for the first time as a novel fusion partner for expression of foreign proteins in an Escherichia coli system. We characterized the expression of recombinant polyhedrin protein fused to green fluorescent protein (GFP). The polyhedrin fusion protein (approximately 58 kDa) was successfully expressed as an insoluble inclusion body comprising approximately 30% of the total cellular protein. The E. coli expressing polyhedrin-GFP fusion protein showed higher cell growth (approximately 1.8-fold) and higher GFP yield (approximately 3.5-fold) than the strain expressing soluble single GFP. Interestingly, the polyhedrin fusion portion showed almost the same characteristics as the native baculoviral polyhedrin; it was rapidly solubilized under alkaline conditions, similar to the conditions found in the insect midgut. In addition, the polyhedrin fusion portion was rapidly digested by alkaline proteases in insect Plutella xylostella midgut as well as by alpha-chymotrypsin, a protease that has similar properties to insect midgut polyhedra-associated alkaline proteases. These unique properties suggest that baculoviral polyhedrin might be an advantageous fusion partner for production of foreign proteins, especially harmful proteins, in E coli expression systems.”
 

INCLUSION BODIES
Definitions: 1. distinctive structures frequently formed in the nucleus or cytoplasm (occasionally in both locations) in cells infected with certain filtrable viruses; may be demonstrated by means of various stains, especially Mann eosin methylene blue or Giemsa techniques and visible by light microscopy. Nuclear inclusion bodies are usually acidophilic and are of two morphologic types: 1) granular, hyaline, or amorphous bodies of various sizes, Cowdry type A inclusion bodies, occurring in such diseases as herpes simplex infection or yellow fever; 2) more circumscribed bodies, frequently with several in the same nucleus (and no reaction in adjacent tissue), the type B bodies, occurring in such diseases as Rift Valley fever and poliomyelitis. Cytoplasmic inclusion bodies may be: 1) acidophilic, relatively large, spheric or ovoid, and somewhat granular, as in variola or vaccinia, rabies, and molluscum contagiosum; 2) basophilic, relatively large, complex combinations of viral and cellular material, as in trachoma, psittacosis, and lymphogranuloma venereum. In some instances, inclusion bodies are known to be infective and probably represent aggregates of virus particles in combination with cellular material, whereas others are apparently not infective and may represent only abnormal products formed by the cell in response to injury. For a list, please see this posting on MedicalGeek.com.
Here are some examples:
http://www.ncbi.nlm.nih.gov/pubmed/22490467
 

E. coli with inclusion bodies
(filamentation response to decompression)
AGROBACTERIUM
[picture of agrobacterium tumefaciens] Morgellons victims may have some agrobacterium T-DNA, which is a soil dwelling bacterium that causes crown gall disease in plants. It is used to create genetically modified (GM) plants by transferring its T-DNA (Ti means Tumor-Inducing) plasmid (with new DNA) into a plant genome. Morgellons patients have tested positive for the presence of Agrobacterium chromosomes (virulence genes and T-DNA on its Ti plasmid) which suggests that genetic engineering has been used in the creation of new disease agents by transferring bacterial genes into humans, exactly as it is being transferred into plant genomes. Fungi, algae, animals and human cells (cancer, neurons and kidney cells) have all been transformed with the Agrobacterium T-DNA. It can cause infections and skin lesions in animals and human beings with compromised immune systems.
[1]http://www.globalresearch.ca/agrobacterium-morgellons-disease-a-gm-connection/9891

Gene Therapy. Agrobacterium is a vector for inserting genes into plant genomes to create transgenic (GM) plants. Transfer requires three major elements: (1) T-DNA border direct repeat sequences of 25 base pairs that flank the T-DNA and delineate the region transferred into the host, (2) the virulence (vir) genes located on the Ti/Ri plasmid, and (3) various genes on the bacterial chromosome. The T-DNA contains oncogenes and genes for synthesizing opines which can be deleted and replaced with genes of interest and selectable markers. [2] Agrobacterium-mediated genetic transformation of plants,

Ecdysone Switch. The steroid hormone 20-hydroxyecdysone, also known as ecdysone, is a hormone which regulates the various stages of development or metamorphosis in many insects. Receptor-Based Gene Switches are used in controlling genes in plants and animals by triggering the “ON/OFF” switch. [2] Kollman (ed.) Ecdysone: From Chemistry to Mode of Action, Thieme Medical Pub., NY (1989)
Switching the agrobacterium genes “ON” tells the transgenes to express the new traits. Various chemicals and steroid analogs such as ponesteroneA and monesteroneA can be used instead of ecdysone. In the following example, the commercial ecdysone agonist (Intrepid-2F/methoxyfenozide) is used and the tobacco mosaic virus (TMV) coat protein (CP) is the gene of interest. [3] See the article: Ecdysone agonist-inducible expression of a coat protein gene from tobacco mosaic virus confers viral resistance in transgenic Arabidopsis  

Binary Biology-Vector Systems.  This system contains two plasmids which can be triggered by the ecdysone inducible system, (1) one plasmid for the unit containing the T-DNA and the origin(s) of replication that could function both in E. coli and Agrobacterium tumefaciens, and antibiotic resistance marker genes used to select for the presence of the binary vector in bacteria. (2) Another plasmid is the “helper” and contains the replicating unit containing the virulence (vir) genes. The “helper” can also be provided by other bacteria, which means that even if the ecdysone switch was not “on”, the genetic changes could take place any way, creating the opportunity for new transgenic pathogens.
Latency. Agrobacterium is very difficult to remove from cell tissues because the binary vector, which contains the foreign genes as well as antibiotic resistance marker genes, can survive in a latent state within cell tissues for many months.

No Limits. THERE IS NO LIMIT TO THE FOREIGN GENES THAT CAN BE INSERTED INTO THE BINARY VECTOR. When viruses are engineered into the T-DNA, new combinations of viruses and the Agrobacterium vector can infect a wide range of hosts that are not normally infected with the virus. NASA talks of making all biology binary which may be only a thought now but with the saturation of the environment and and humans with biological aerosols, there is a real possibility of doing so. [5] [insert reference here]
 

Filamentation of B. subtilis


PROOF OF BIOSYNTHETIC
FILAMENTATION VIA SYNTHETIC SWITCH
This articles shows that a genetic toggle switch (created with synthetic biology) can activate filamentation by inhibiting a cell division inhibitor. If you stop division of the cell, it lengthens into filaments colored with green fluorescent proteins which by the way can be genetically changed to yellow, blue, orange and purple.
COLOR CODING FLUORESCENT PROTEINS
The technology for genetically color-coding bacterial protein products is presented in the following power point presentation:
Peter G. Schultz PPT Presentation
A Genetically Encoded Fluorescent Amino Acid
Following is the scientific article explaining the placement of unnatural amino acids in Green Fluorescent Protein to change the spectral length, thus making it a different color. These structures are put in the genetic code of the microbes (bacteria) which produce a colored protein product.
Unnatural Amino Acid Mutagenesis of
Green Fluorescent Protein
 

SEGMENTED FILAMENTOUS BACTERIA
Internet Picture by Alice Liang, NYU and
Doug Wei, Carl Zeiss; artificial coloring by Eric Roth, NYU
Segmented filamentous bacteria or Candidatus Savagella are members of the gut microbiota of rodents, fish and chickens, and have been shown to potently induce immune responses in mice. Segmented Filamentous Bacteria are species specific, and may be important to immune development.
 

FILAMENTOUS FUNGI
Molds are fungi that grow in the form of multicellular filaments called hyphae. A connected network of these tubular branching hyphae, called a mycelium, is considered a single organism. The hyphae are generally transparent, so the mycelium appears like very fine, fluffy white threads over the surface. Cross-walls (septa)separate connected compartments along the hyphae, each containing one or more, genetically identical nuclei. The dusty texture of many molds is caused by profuse numbers of asexual spores called conidia formed by differentiation at the ends of hyphae. The shape, color and the way they are formed are used to classify the fungi.

Fungi that can adopt a single celled growth habit are called yeasts. Molds are considered to be microbes and do not form a specific taxonomic or phylogenetic grouping, but can be found in the divisions Zygomycota and Ascomycota. Molds biodegrade natural materials. They also play important roles in biotechnology and food science in the production of various foods, beverages, antibiotics, pharmaceuticals and enzymes. Some diseases of animals and humans can be caused by molds as a result of allergic sensitivity to their spores or toxic compounds.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2696486/
 

FILAMENTOUS ORGANISMS
Below is some information from the internet pulled together for your convenience in examining the possible origins of filamentous organisms. I have noticed that some specimens one might think are fibers are actually some type of worm so that’s another possibility for things that look like fibers.

FILAMENTATION
Why Do Bacteria Filament?
February 04, 2008
http://tinyurl.com/bwrfzkz
Streptomyces coelicolor (false   colored).
Source: Nora Ausmees, University of Uppsala
Some bacteria naturally grow as filaments, e.g.,  members of the actinomycetes. Many others, e.g.,  E. coli and B. subtilis, make filaments only when under stress─a fact that has been known for about one hundred years but is still a bit of a mystery.

Many kinds of stress can prompt this response, including DNA damage that elicits the SOS response, partial inhibition of cell wall synthesis by antibiotics, and the expression of certain thermosensitive mutations affecting cell division (called fts mutants for “filament forming temperature sensitive”). So general is this phenomenon that, over 30 years ago, we commented in a review: …it seems possible that any chemical at some concentration, whether attainable in the laboratory or not, can cause filament formation. (When the great geneticist, Rollin Hotchkiss, heard of this, he muttered: How depressing!) Be that as it may, filamentation is to bacteria what fever is to children.

Ultrathin section of an E. coli temperature-sensitive mutant grown at 42° for 45 minutes. Scale bar: 1mm. Source: Burdett, I. D. J. and R. G. E. Murray. 1974. Septum Formation in E. coli. J. Bacteriol. 119: 303-324Filaments, in both bacteria and fungi, result when rod-shaped cells cease to divide but continue to grow. In many cases, growth can continue for quite a while and at a rapid speed, resulting in long and often healthy-looking filaments. Nucleoids continue to segregate and are spaced normally along the filament. (Some folks like to call this polyploidy, but multinucleate seems more appropriate.) Apparently, under some circumstances, cell division is a dispensable process─at least for a while.

Schematic drawing of a mutant defective in decatenation of progeny chromosomes. The DNA does not segregate but remains as a mass in the center of the cell. Source: Schaechter, M., J. L. Ingraham, and F. C. Neidhardt. 2006. Microbe p.182.

To show how indifferent cell growth can be to whether a cell divides or not, cells also become filamentous when decatenation of their intertwined progeny chromosomes is inhibited by mutation or by drugs. Given the pleiotropic nature of the response, it has proven difficult to figure out why cell division is so much more delicate than the rest of the cell’s functions.For now, let’s leave questions of mechanism aside and ask instead, how this phenomenon matters in the ecology of these organisms. This question has recently been examined in an article from Scott Hultgren’s lab. The article goes a long way towards making sense of why bacteria might have developed such a strategy. It is pleasurable reading, illustrated with many exciting instances. Their examples suggest that filamentation can confer protection against grazing predators (including phagocytes in mammalian hosts), resistance to intracellular killing, swarming motility to evade immune cells, and insensitivity to some antibiotics and other inimical agents. Making filaments to avoid grazing by predatory protists is often seen in marine and other environments. In general, bacteria longer than 7 μm are inedible by many protists, and filamentation occurs in direct response to effectors produced by the predators. In other cases, e.g., in some Proteus, filamentation is part of their life cycle. These organisms “swarm” intermittently on agar as well as on the surface of catheters. The pathogenic E. coli that cause urinary tract infections invade the epithelial cells of the bladder, and there they transform into filaments some 50 times the normal length. This strategy enables these filamenting bacteria (and others) to survive engulfment by phagocytic cells. Also, at body temperatures, Legionella make phagocytosis-resistant biolfilms composed of filamentous cells.

Filamentous E. coli on infected mouse bladder cells. The bacteria were stained with a red fluorescent nucleic acid dye (ToPro3) and examined under a laser scanning confocal fluorescent microscope. Scale bar:  30 μm. Source: Justice,  S. S., D. A. Hunstad, P. C. Seed, and S. J. Hultgren. 2006. Filamentation by E. coli subverts innate defenses during urinary tract infection. PNAS 103(52) 19884-19889.After completing their extensive survey, the authors conclude that filamentation is a survival tactic employed by diverse bacteria under a variety of conditions. Considering the reliance of some pathogens on filamentation, they suggest that drugs blocking filament formation may be useful against specific pathogens. We thank the authors for calling attention to the broad ecological aspects of this distinctive bacterial (and fungal) talent. I finish with an aside: the opposite of filamentation, i.e., division without growth, also occurs. In the lab, bacterial cells in stationary phase are generally smaller than growing ones. Likewise, most bacteria making a living in oligotrophic environments are on the small side, some so small as to merit the label nanobacteria. I recall once observing under the microscope the “growth” of E. coli on purified agar containing only phosphate buffer. Each cell divided three or four times, resulting in an average cell size 1/8 to 1/16 of the starting one! Filaments count, but so do numbers.

After completing their extensive survey, the authors conclude that filamentation is a survival tactic employed by diverse bacteria under a variety of conditions. Considering the reliance of some pathogens on filamentation, they suggest that drugs blocking filament formation may be useful against specific pathogens. We thank the authors for calling attention to the broad ecological aspects of this distinctive bacterial (and fungal) talent. I finish with an aside: the opposite of filamentation, i.e., division without growth, also occurs. In the lab, bacterial cells in stationary phase are generally smaller than growing ones. Likewise, most bacteria making a living in oligotrophic environments are on the small side, some so small as to merit the label nanobacteria. I recall once observing under the microscope the “growth” of E. coli on purified agar containing only phosphate buffer. Each cell divided three or four times, resulting in an average cell size 1/8 to 1/16 of the starting one! Filaments count, but so do numbers.

http://en.wikipedia.org/wiki/Filamentation Bacteria have complex systems to protect themselves but they alter this highly regulated process to transform into filamentous organisms in stressful environments, including sites of interaction with their hosts. Filamentation could be a response to specific environmental cues that promote survival amidst the threats of consumption and killing. In E. coli, cells continue to elongate but do not divide (no septa formation). Filamentation may be a reaction to DNA damage or inhibition of replication involving the SOS response which has been proposed as a model for bacterial evolution of certain types of antibioticc resistance. The SOS response elicits filamentation.

Filamentation of E. coli.

BIOSYNTHESIS OF FIBERS
One study on four Morgellons victims describes some Morgellons fibers as being keratin and collagen and they form as a result of stimulation.[6] [Put reference here] No explanation for the sudden production of keratin and collagen products is provided in this study. Why would healthy skin suddenly become hyperkeratinized?  Would it occur after an insect injected foreign materials, including eggs in to the skin? 
The foreign organisms will be living their life cycle or a part of their life cycle in the skin which includes eating, digestion, excretion, reproduction and byproducts thereof. The presence of bacteria in the reproductive tracts and gut of the arthropods that lay eggs in the skin is an indication that there will be a product produced by the bacteria and fungus.
One sources of information on fibers from Morgellons victims have stated that the fibers are polyethylene. This would make one assume they are not “natural” but engineered some way to create a sturdy fiber, resistant to heat. It is been circulated that some fiber didn’t burn until 1700o. You can’t assume this is true. The person or organization that put this information out would have to be questioned as to their accuracy in studying an unidentified fiber. Who identified the fiber as polyethylene and did they have the knowledge or correct procedures to correctly identify the fiber? There are many types of fibers so you can’t assume we’re always talking about the same fiber. You have to exercise caution when you begin with a supposition. The identification as a particular plastic might depend on who is identifying the plastic and their method of identification and whether it was based solely on scientific method.
One Morgellons study found 6 bacteria. Bacteria is known to possess the amazing ability to create plastic and metal, even gold. Consider the following:
 

Expanding the Genetic Code for Biological Studies.
Summary.  Using an orthogonal tRNA-synthetase pair, unnatural amino acids can be genetically encoded with high efficiency and fidelity; and over forty unnatural amino acids have been site-specifically incorporated into proteins in E. coli, yeast, or mammalian cells. Novel chemical or physical properties embodied in these amino acids enable new means for tailored manipulation of proteins. This review summarizes the methodology and recent progress in expanding this technology to eukaryotic cells. Applications of genetically encoded unnatural amino acids are highlighted with reports on labeling and modifying proteins, probing protein structure and function, identifying and regulating protein activity, and generating proteins with new properties. Genetic incorporation of unnatural amino acids provides a powerful method for investigating a wide variety of biological processes both in vitro and in vivo.
 

FOOTNOTES:
(1)  BioBrick standard biological parts are DNA sequences of defined structure and function; they share a common interface and are designed to be composed and incorporated into living cells such as E. coli to construct new biological systems. A registry of several thousand public domain BioBrick parts is maintained by Randy Rettberg team at http://partsregistry.org.

(3)  VERY IMPORTANT. THIS IS THE SWITCH USED TO TRIGGER GENE THERAPY:
The ecdysone receptor is a nuclear receptor found in arthropods where it controls development and contributes to other processes such as reproduction. Gene switches – ecdysone receptor-controlled transgenes for controlled gene expression in scientific research, agriculture, and gene therapy. Here’s one method using lentivirus.
http://www.nature.com/mt/journal/v11/n1/full/mt200518a.html
Development of Ecdysone-Regulated Lentiviral Vectors
To achieve gene regulation in mammalian cells without interfering with endogenous steroid hormones and mammalian nuclear receptors, the Drosophila ecdysone receptor (EcR) has been used to build an ecdysteroid-responsive gene switch. The resulting system has been optimized to achieve maximal gene expression.

(4) Excerpt from “Expanding the Genetic Code”By T. Ashton Cropp and Peter G. Schultz
Protein Synthesis: How can the system be altered to incorporate unnatural amino acids?
More than 30 novel amino acids have been genetically encoded in response to unique triplet and quadruplet codons including fluorescent, photoreactive and redox active amino acids, glycosylated and heavy atom derived amino acids in addition to those with keto, azido and acetylenic chains. It is possible to add new building blocks systematically to the genetic codes of bacteria, yeast and mammalian cells. Taken together these tools will enable the detailed investigation of protein structure and function, which is not possible with conventional mutagenesis. By lifting the constraints of the existing 20-amino-acid code, it should be possible to generate proteins and perhaps entire organisms with new or enhanced properties.

[This technology has been patented and is being included in all forms of life, including mammals. It is meant not to replace biology but to exist alongside it. I believe it has been included in Morgellons.

Compositions of orthogonal lysyl-tRNA and aminoacyl-tRNA synthetase pairs and uses thereof United States Patent 757589 http://www.freepatentsonline.com/7575895.html
An update on the Scripps website show 71 new novel unnatural amino acids]
 

WHAT IS TESSY?